Substance use disorder (SUD) affects millions of individuals and presents unique clinical, ethical and interpersonal challenges in dental practice. This program provides dental professionals with the tools to recognize the oral manifestations of SUD, manage treatment compassionately, and navigate the complexities of care coordination, relapse risk and stigma. From the dental implications of “new” opioids, to synthetic cannabinoids and emerging illicit use of licit medications, participants will explore evidence-based approaches to providing non-judgmental, effective dental care to this vulnerable population.