Modern prevention requires closer collaboration between medicine and dentistry. This lecture explores how dentists and dental hygienists can identify oral findings associated with cardiometabolic risk, vascular inflammation and early systemic disease. Using clinical examples, Dr. Reisinger examines periodontal disease, dental infection, airway compromise, and oral inflammation and their potential links to systemic health. Practical tools—including salivary diagnostics, CIMT, coronary artery calcium scoring, inflammatory biomarkers and chart review—will be discussed, along with strategies for physician-dental collaboration, referrals, communication and integrated preventive care.